2,3-cGAMP-iFluor 488 conjugate

2,3-cGAMP-cGAMP-iFluor 488 conjugate can detect cGAMP or monitor its activity.The iFluor 488 conjugate is brighter and has higher photostability than the fluorescein conjugate. In addition,the fluorescence of iFluor 488 is not affected by pH (4-10).2,3-cGAMP has received widespread attention in recent years due to its potential as a therapeutic target for diseases such as cancer and viral infections. It has been proven to activate the immune system and enhance the efficacy of immune checkpoint inhibitors, which is a cancer immunotherapy. 2,3-cGAMP(cyclic GMP AMP) is a cyclic dinucleotide second messenger molecule that plays a crucial role in the innate immune system. 

msds of 2,3-cGAMP-iFluor 488 conjugate